Early research shows that taking vitamin C might reduce the

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This screening assessment was prepared by staff in the Existing Substances Programs at Health Canada and Environment and Climate Change Canada and incorporates input from other programs within these departments. The ecological portions of this assessment have undergone external written peer review/consultation. Approaches used in the screening assessments under the Challenge have been reviewed by an independent Challenge Advisory Panel.

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An additional search was performed in the Cochrane Database of Systematic Reviews for corticosteroids and the following text words: traumatic injury, sepsis/septic shock, meningitis, bronchopulmonary dysplasia, liver diseases steroids, lung diseases and rheumatoid arthritis. Only results fully reported in journal articles in English, German or any Scandinavian language were considered for inclusion. Whenever a title or abstract suggested that a randomised, double blind, placebo controlled trial comparing a corticosteroid to placebo had been performed, the full text version was reviewed for documentation of GI adverse events.

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